Vacancies

Research position Time-of-Flight PET imaging at Ghent university (Belgium)

Job description

The MEDISIP research group is searching for a highly motivated and talented person for research on Time-of-Flight PET. MEDISIP (MEDical Image and SIgnal Processing) is an iMinds research group, part of the faculty of engineering of Ghent University. The team consists of 25 researchers, active in the field of medical imaging science and multimodality imaging. MEDISIP is located at the University Hospital (UZ Ghent) and has ongoing collaborations with hospitals, research groups and industry all over the world. During the last years significant part of the research work has focused on time-of-flight PET and multimodality PET.

Description

  • You will work on a project for imaging non-standard isotopes in advanced PET scanners
  • You will develop quantitative image reconstruction with advanced corrections
  • You will apply these methods on dosimetry of therapeutic isotopes
  • You will participate in conferences and publish results in scientific literature

Profile of the candidate

  • You have a Masters of Science degree, preferably in Biomedical Engineering, Physics, Electrical Engineering, Electromechanical Engineering from a European university
  • You will apply for a personal PhD grant at IWT (deadline 15 september)
  • You have a large interest in medical imaging
  • You are a collaborative dynamic person who prefers a multidisciplinary research environment
  • You have good communication skills (written and oral) in English
  • Experience in simulations, measurements and reconstruction for PET or SPECT is an asset.

How to apply

Applicants should send their application (motivation letter +CV + 2 references to Stefaan.Vandenberghe@ugent.be). Candidates with an interesting profile will be contacted for an interview (skype for international candidates). The position will remain available until until a suitable candidate has been found.

 

Two PhD Positions in biomedical neurosciences and biomedical engineering at Ghent University (Belgium)

The Department of Neurology at Ghent University (Belgium) is seeking to fill two PhD positions in preclinical epilepsy research and small animal functional imaging. The fellows will join a research project situated in the context of an interdisciplinary research partnership between the Laboratory for Clinical and Experimental Neurophysiology, Neurobiology and Neuropsychology (LCEN3, headed by Prof. dr. Paul Boon) and the INFINITY lab (http://www.infinityugent.be; headed by Prof dr. Chris Vanhove) on imaging and modulating abnormal brain networks in the epileptic rodent brain.

This preclinical research project includes small animal functional Magnetic Resonance Imaging (fMRI), video-EEG monitoring, intracranial electrophysiology, signal analysis, deep brain stimulation (DBS), drug therapy, chemogenetics (DREADDs) and optogenetics in rodent models for epilepsy. Applicants should have a background in biomedical sciences, biomedical engineering or related discipline and have a strong interest in the domain of animal research, electrophysiology and/or fMRI data analysis. Applicants should be collaborative, dynamic persons who like to work in a multidisciplinary research environment. Applicants should have good knowledge of the English language and good communication skills (written and oral). Candidates will be selected based on excellent study results, motivation, good scientific reasoning and recommendation letters by previous supervisors.

The department of Neurology of Ghent University and INFINITY lab offers access to several preclinical models for epilepsy research and several preclinical research techniques, including state-of-the-art in vivo neuroimaging techniques (small animal fMRI, µPET, µSPECT, µCT, optical imaging), stereotactic neurosurgery, in vivo and in vitro neurophysiological recording and neurostimulation techniques, in vivo(stem) cell and gene therapy (including optogenetics and chemogenetics).

Both PhD positions will be open for four years with starting date between May 2017 and October 2017.

Interested candidates should send a CV, motivation letter, and two reference letters to this email address: Robrecht.Raedt@ugent.be.

 

PhD Position on Development of 188Re-based radiopharmaceuticals for theranostic treatment of melanoma

Job description
This doctoral research project has the aim to develop and validate radionuclide therapy for the treatment of metastatic melanoma (both primary tumour and metastatic lesions) by 188Re-labelled carrier molecules based on quantitative imaging and dosimetry. At the end of this project, we intent to have preclinically validated 188Re-labelled carrier molecules for theranostic treatment of melanoma.

This research project will be conducted by the Radiochemistry group (RCA) of the Belgian Nuclear Research Centre (SCK•CEN) and the IMIT (Innovative Molecular Imaging and Therapy) consortium of the University of Gent (UGent). RCA will provide the 188Re isotope and develop stable 188Re-labelled carrier molecules. UGent will provide the carrier molecules and perform preclinical evaluation of the 188Re-labelled carrier molecules by in vitro and in vivo characterisation. In a later stage of the project, in vitro and in vivo characterisation could be complemented by analogous studies performed at SCK•CEN.

Profile of the candidate

  • The person should have a master in the field of biomedical engineering/biomedical sciences/pharmaceutical sciences/biochemical/Bio engineering or equivalent
  • Knowledge of radiobiology is a plus
  • Knowledge of radiochemistry, especially radiolabelling, is a plus
  • Knowledge of imaging, is a plus
  • Experience with in vitro/in vivo experiments is a plus
  • Good skills in performing (bio-)chemical and biomedical experiments
  • Ability to work in an interdisciplinary and collaborative environment
  • Ability to write clear scientific reports and disseminate results
  • Good oral, interpersonal and written communication skills
  • Creative and self-motivated
  • Committed to achieve objectives and overcoming obstacles
  • Committed to safe working and operational procedures

How to apply and more information
http://academy.sckcen.be/en/Your_thesis_internship/AllTopics/Development-of-188Re-based-radiopharmaceuticals-for-theranostic-treatment-of-melanoma-1667